
Thermaltake SMART 750W SP-750P Overview
An in depth look at the SMART 750W SP-750P power supply from Thermaltake.
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Key Protein for Alzheimer's Identified
The illnesses of old age are possibly something many of us have experience with, as family members have developed them. Alzheimer's is perhaps one of the better known and more destructive of these illnesses. Researchers at the Yale School of Medicine have recently discovered a protein that connects two steps that lead to Alzheimer's.
Through years of work, scientists have managed to create a partial molecular map for the path Alzheimer's takes to destroy brain cells. One of the missing parts was concerned with how a coupling of a peptide with a prion would lead to the activation of a messenger molecule called Fyn. The Yale researchers have found that a protein called metabotropic glutamate receptor 5, or mGluR5, is involved in that process. By blocking it in mice with brain damage similar to that caused by Alzheimer's, the researchers found that the mice recovered their deficits in memory, learning, and synapse density.
As it happens, the drug used to block mGluR5 is similar to one in development for Fragile X syndrome, though a new drug will likely have to be created specifically for treating Alzheimer's. Once found though, a great many individuals and families could find relief from this devastating disease.
Source: Yale University
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Hardware Roundup: Monday Edition
Intel's new Core i7 4960X Extreme Edition processor is the top dog in the market right now, and we have another review showing it off. This review also decides to do a little bit of extreme overclocking with an LN2 pot to see just how far the chip can go, so it's definitely something you won't want to miss. We have a look at the SilverStone SST-TD03 all-in-one liquid CPU cooler, which is the company's first foray into that particular cooling segment. Rounding things off is the Vampire case from Raidmax that's pretty massive and packed to the gills with all sorts of features to make your next build an easy one.
CPUs
Intel Ivy Bridge-E 4960X CPU (LN2 inside) @ Madshrimps
CPU Cooling
SilverStone SST-TD03 All-In-One Liquid CPU Cooler @ Benchmark Reviews
Cases
Raidmax Vampire Full Tower @ ThinkComputers
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